‘Mastectomy’ surgery can reduce the mortality rate due to breast cancer in women.

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Toronto: Research has shown that women with BRCA1 or BRCA2 genetic variants may be less likely to die if they undergo mastectomy (a surgical procedure in which all or part of the breast is removed). The study, published in the British Journal of Cancer, looked at how risk-reducing ‘mastectomy’ affects the mortality rate of those women. Women who have an inherited BRCA1 or BRCA2 variant have an 80 percent risk of developing breast cancer in their lifetime.

Research has shown that ‘mastectomy’ reduces the risk of breast cancer by 90 percent. Professor Kelly Metcalf of the University of Toronto, Canada, said: “Making the decision to have a risk-reducing mastectomy is often difficult for a woman, and when they are making that decision, we provide them with more information so that they can take better care of themselves.” Can do from.

He said 30 per cent of women with the pathogenic variant in Canada opt for this surgery. It is one of the most effective ways to prevent breast cancer in women with this risk profile. In a trial, Metcalf and his team followed more than 1,600 women with pathogenic BRCA1/2 variants from nine different countries over the course of six years, half of whom had a risk-reducing mastectomy.

At the end of the trial there were 20 breast cancer cases and 2 deaths in the group choosing ‘mastectomy’ and 100 breast cancer cases and 7 deaths in the control group. Mastectomy reduced the risk of breast cancer by 80 percent, and the chance of dying from breast cancer 15 years after a risk-reducing ‘mastectomy’ was less than one percent.

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