Some diabetes medicines can reduce the risk of kidney stones
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New York: Some diabetes medications can reduce the risk of kidney stones. According to a study, type 2 diabetes is associated with an increased risk of kidney stones. Some types of treatment for this condition may also be beneficial in reducing the risk of kidney stones. Researchers at Brigham and Women’s Hospital and Massachusetts General Hospital in the US found that there was an association between the use of sodium-glucose contratransporter 2 (SGLT2) inhibitors and a reduced risk of developing kidney stones. The study, reported in JAMA Internal Medicine, included data from three nationwide databases in the United States of patients with type 2 diabetes who were seen in routine clinical practice.
The team analyzed information from 716,406 adults with type 2 diabetes. who had started taking SGLT2 inhibitors or two other classes of diabetes drugs known as GLP1 receptor agonists or dipeptidyl peptidase 4 (DPP4) inhibitors. Patients who started taking SGLT2 inhibitors had a 30 percent lower risk of developing kidney stones than those taking GLP1 agonists and about 25 percent lower than those taking DPP4 inhibitors. These findings were consistent across gender, race/ethnicity, history of chronic kidney disease, and obesity. “Our findings may help inform routine decision-making for diabetic patients who are at risk of developing kidney stones,” said study author Julie Pike.
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